NOTEBOOK

The Digitalis Notebook contains our writing on the ideas that underpin the work of Digitalis Ventures, Digitalis Commons, and Digitalis Labs.

May 27, 2026

The Proximate and the Possible

Biomedicine has never lacked for miracles. The harder question is who they're for.

Geoffrey W. Smith

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April 29, 2026

The Logic of the Commons: Why Communities in Health Form, Fracture, and Sometimes Flourish

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April 22, 2026

Old Dogs, New Tricks: Managing Osteoarthritis in Pets

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March 25, 2026

The Healthcare Market Cannot Heal Itself: Notes on Health, Markets, and Power

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February 25, 2026

Beyond Boundaries: Rebuilding the Architecture of Knowledge

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February 19, 2026

Longevity for Pets. What Really Works?

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January 27, 2026

Endogenous Technological Change

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December 18, 2025

ICYMI 2025 Edition

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December 11, 2025

A Natural History of Pets

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November 25, 2025

The Error Bar: Notes on a Visual Grammar of Uncertainty

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October 30, 2025

Mind the Rule Gap

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October 15, 2025

A Rabies Resurgence?

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September 25, 2025

Funding the Unfundable

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August 29, 2025

On Protocols

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August 18, 2025

Notes on Animal Health, August 2025: Is Better Breeding Best?

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July 29, 2025

On Patents, Licenses, and Moral Gatekeepers of Biotech Innovation

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June 25, 2025

On Randomness

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June 10, 2025

Sweating Like a Pig

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May 28, 2025

On Contracts

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April 29, 2025

On Quantum Biology

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April 11, 2025

Notes on Animal Health, April 2025: Who Doesn’t Get Cancer?

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March 31, 2025

On Recursion

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February 25, 2025

On the Flu

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February 14, 2025

A Veterinary Fenomenon

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January 28, 2025

On Biological Speed Limits

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December 23, 2024

ICYMI 2024 Edition

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December 13, 2024

Is the Promise of Stem Cells Finally Being Realized?

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November 26, 2024

On Value Capture

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October 30, 2024

On Risk, Uncertainty, AI & Entrepreneurs

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October 9, 2024

Notes on Animal Health, August 2024: Would You Clone Your Dog? Should You?

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September 30, 2024

On Biology and Geometry

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August 28, 2024

On Morphogenesis

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August 14, 2024

Notes on Animal Health, August 2024: When You’re Allergic to the One You Love

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July 30, 2024

On Unconventional Computing

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June 27, 2024

On Environmental Health

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June 17, 2024

Can You Really Outrun a Horse?

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May 30, 2024

On Pharmacies

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April 30, 2024

On Radiopharmaceuticals

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April 19, 2024

Notes on Animal Health, April 2024: Pets are Good for Us, but are We Good for our Pets?

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March 28, 2024

On Providers

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February 29, 2024

On Academic Publishing

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February 9, 2024

A Matter of Heart

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January 30, 2024

On Pharmacy Benefit Managers

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December 27, 2023

ICYMI 2023 Edition

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December 19, 2023

Notes on Animal Health, December 2023: Pets vs. Pests

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November 30, 2023

On How We Drug The Brain

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October 31, 2023

On Payers

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October 20, 2023

One Health

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September 29, 2023

On Frailty

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August 31, 2023

On Seeing Biology

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July 31, 2023

On Heat and Humidity

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June 28, 2023

On Women’s Health

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May 20, 2023

Notes from Jacob Oppenheim & Travis Hughes

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April 28, 2023

On Xenotransplantation

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March 31, 2023

On Employer-Sponsored Health Insurance

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February 28, 2023

Some Notes on Fermentation

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February 28, 2023

On Fermentation

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January 30, 2023

This Text Was NOT Written by AI

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December 30, 2022

ICYMI 2022 Edition

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November 29, 2022

On Public Health: Between Populations & Communities

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October 31, 2022

Some Digitalis Ventures News

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September 29, 2022

Nature, Nurture, & Good Luck

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August 31, 2022

Risky Business

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July 31, 2022

On Creativity

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June 30, 2022

Abortion is Healthcare

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May 31, 2022

Life, the Universe, and Everything

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April 30, 2022

The Time of Your Life

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March 31, 2022

Lampposts and Genomics

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February 28, 2022

Some Random Thoughts

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January 31, 2022

On Human Breastmilk & Personalized Nutrition

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December 31, 2021

ICYMI 2021 Edition

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November 30, 2021

Surprise Billing: A Personal Story

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October 31, 2021

Nucleate: Empowering Biotech Founders

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September 30, 2021

On the Privacy and Security of Electronic Health Information

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August 31, 2021

Evolution and Public Health

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July 31, 2021

On Model Organisms

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June 30, 2021

XX Versus XY

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May 31, 2021

The Ends, Not the Means

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April 30, 2021

A Fertile Ground for AI Companies

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March 31, 2021

A Short History of the EMR

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February 28, 2021

Climate and Health

essays

MAY 27, 2026

The Proximate and the Possible

essays

APRIL 29, 2026

The Logic of the Commons: Why Communities in Health Form, Fracture, and Sometimes Flourish

essays

MARCH 25, 2026

The Healthcare Market Cannot Heal Itself: Notes on Health, Markets, and Power

essays

FEBRUARY 25, 2026

Beyond Boundaries: Rebuilding the Architecture of Knowledge

essays

JUNE 16, 2025

Revitalizing US Biomanufacturing to Strengthen the Global Supply and Security of Antibiotics

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MARCH 8, 2025

Unlocking Investment for Women’s Health

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JANUARY 2, 2025

Should There be Profit in Knowledge?

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Endogenous Technological Change.

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The general idea of a “rule” can be understood to encompass a wide-range of things including statutes, regulations, common law, guidelines, contracts, norms, corporate policies, and unspoken practices. At the intersection of health and technology, each of these rule categories applies, and each has tangible effect on health outcomes.

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Design is an essential layer in most endeavors that aim to improve health, though far too often there is a failure to plan for, finance, and deploy design solutions.

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The advent of new technologies often outstrips our existing ethical and equity frameworks. Society is then forced to revisit basic normative issues such as the boundaries of privacy, the role of intellectual property, and even the definition of humanity.

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How do issues related to health, environment, and food intersect to produce more or less security at the level of individuals?

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